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anti-Mouse (Murine) PPP2R1A Antibodies:
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Human Polyclonal PPP2R1A Primary Antibody for WB - ABIN1881682
Jones, Wang, Shih, Mao, Nakayama, Roden, Glas, Slamon, Diaz, Vogelstein, Kinzler, Velculescu, Papadopoulos: Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. in Science (New York, N.Y.) 2010
Show all 5 Pubmed References
Human Polyclonal PPP2R1A Primary Antibody for IP, WB - ABIN188577
Quintela-Fandino, Arpaia, Brenner, Goh, Yeung, Blaser, Alexandrova, Lind, Tusche, Wakeham, Ohashi, Mak: HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. in Proceedings of the National Academy of Sciences of the United States of America 2010
Human Polyclonal PPP2R1A Primary Antibody for ELISA, IHC - ABIN250350
Hong, Sarge: Regulation of protein phosphatase 2A activity by heat shock transcription factor 2. in The Journal of biological chemistry 1999
oocyte-specific deletion of Ppp2r1a led to severe female subfertility without affecting follicle survival, growth, and ovulation.
A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.
PP2A (show PPP2R2B Antibodies) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (show PLK4 Antibodies) autophosphorylation, thus stabilizing Plk4 (show PLK4 Antibodies) and promoting centriole duplication
PP2A (show PPP2R2B Antibodies)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (show TFAP2A Antibodies), CREB (show CREB1 Antibodies), ETS-1 (show ETS1 Antibodies), and SP-1 (show SP1 Antibodies)
Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.
protein phosphatase 2A overexpression in NIH 3T3 cells
T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (show PPP2R2B Antibodies) prevents the inhibitory function of CTLA-4 (show CTLA4 Antibodies), before TCR-CTLA-4 (show CTLA4 Antibodies) coligation.
PP-2A regulation of paxillin (show PXN Antibodies) phosphorylation may have a role in controlling tumor cell adherence and motility.
PP2A (show PPP2R2B Antibodies) may contribute to melanoma cell radioresistance: the truncated isoform of the PP2A (show PPP2R2B Antibodies) B56gamma regulatory subunit reduces irradiation-induced Mdm2 (show MDM2 Antibodies) phosphorylation
PP2A (show PPP2R2B Antibodies) has a fundamental role in cardiac function
PPP2R1A mutations occur in a subset of gastrointestinal stromal tumors and are associated with a high malignant potential that leads to decreased disease-free survival and overall survival
Results demonstrated that the promotive effect of eEF-2K (show EEF2K Antibodies) on glycolysis resulted from the kinase-mediated restriction of synthesis of the protein phosphatase 2A-A (PP2A (show PPP2R4 Antibodies)-A).
PPP2R1A mutation is associated with endometrial carcinoma progression and abdominopelvic metastasis.
PPP2R1A mutations affect PP2A (show PPP2R4 Antibodies) function and oncogenic signaling, illuminating the genetic basis for serous EC development.
PR65A phosphorylation regulates PP2A (show PPP2R4 Antibodies) complex signaling.
Our results suggest that IH-induced ROS (show ROS1 Antibodies) generation increases PP2A (show PPP2R4 Antibodies) activation and subsequently downregulates ERK1/2 activation, which results in inhibition of PC12 cell proliferation through G0/G1 phase arrest and NGF (show NGFB Antibodies)-induced neuronal differentiation.
The two functional variants in PPP2R1A and PPP2R5E (show PPP2R5E Antibodies) and their combinations are associated with lung cancer risk in the Chinese.
Partial unfolding of PR65/A impacts catalysis by altering the proximity of bound catalytic subunit and substrate.
For PPP2R1A, a heterozygous, somatic mutation (c.771G>T, p.W257C) was identified in 1 out of 37 patients (2.7%) with primary ovarian endometrioid carcinoma.
gene transcription of PPP2R1A regulated by the polymorphism and methylation in the promoter region
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform
, platelet-derived growth factor subunit B
, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
, alpha isoform of regulatory subunit A, protein phosphatase 2
, protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform
, protein phosphatase 2, regulatory subunit A, alpha
, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like
, PP2A subunit A isoform PR65-alpha
, PP2A subunit A isoform R1-alpha
, protein phosphatase PP2A
, serine/threonine protein phosphatase A subunit type 2A
, protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
, medium tumor antigen-associated 61 KDA protein
, serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform
, medium tumor antigen-associated 61 kDa protein
, protein phosphatase 2A 65 kDa regulatory subunit, alpha isoform