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|Antigen||Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||Alexa Fluor 594 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human AXUD1|
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|Alternative Name||AXUD1 (CSRNP1 Antibody Abstract)|
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].
Synonyms: Axin 1 Up-regulated, Axin-1 up-regulated gene 1 protein, CSRN1_HUMAN, CSRNP-1, CSRNP1, Cysteine/serine-rich nuclear protein 1, DKFZp566F164, FAM130B, Protein URAX1, TAIP 3, TAIP-3, TGF beta induced apoptosis protein 3, TGF-beta-induced apoptosis protein 3, URAX1.
|Research Area||Chromatin and Nuclear Signaling, Cell Cycle, Apoptosis/Necrosis|
|Pathways||Platelet-derived growth Factor Receptor Signaling|
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|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
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|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|