anti-Mouse (Murine) BRE antibody for Enzyme Immunoassay

Recommended BRE Antibody

Antigen
Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) Antibodies
  • brcc4
  • brcc45
  • BRE
  • LOC100231620
  • BRCC4
  • BRCC45
  • 6030405P19Rik
  • AI429776
  • B830038C02Rik
  • im:7141046
  • zgc:110368
  • BRISC and BRCA1 A complex member 2
  • brain and reproductive organ-expressed (TNFRSF1A modulator)
  • BRISC and BRCA1 A complex member 2 L homeolog
  • babam2
  • BABAM2
  • Babam2
  • BRE
  • babam2.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
71
48
40
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
68
3
Clonality
Polyclonal
Conjugate
This BRE antibody is un-conjugated
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
24
24
18
17
13
10
4
3
1
1
1
1
Options

Available images

Catalog No. ABIN372906
$ 495.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN5554628 EIA IHC (p) WB Rabbit IgG N-Term Polyclonal 0

General

Antigen Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(71), (48), (40), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(68), (3)
Clonality
Polyclonal
Conjugate This BRE antibody is un-conjugated
(2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(50), (24), (24), (18), (17), (13), (10), (4), (3), (1), (1), (1), (1)
Supplier

Product Details anti-BRE Antibody

Target Details BRE Application Details Handling Images
Specificity This antibody reacts to Brain And Reproductive Organ-expressed Protein (BRE).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide
Isotype IgG
Plasmids, Primers & others

Target Details BRE

Product Details anti-BRE Antibody Application Details Handling Images back to top
Antigen
Alternative Name BRE / BRCC45 (BRE Antibody Abstract)
Background BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs. Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36. This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage. BRCC45 has also been suggested to function as a death receptor associated anti apoptotic protein by inhibiting the BID induced activation of the mitochondrial apoptotic pathway. Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, suggesting that BRCC45 may promote tumorigenesis when overexpressed. At least three isoforms of BRCC45 are known to exist.Synonyms: BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, BRCC45, BRE, Brain and reproductive organ-expressed protein
Gene ID 9577
NCBI Accession NP_004890
UniProt Q9NXR7
Pathways Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-BRE Antibody Target Details BRE Handling Images back to top
Application Notes Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1 - 2 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BRE Antibody Target Details BRE Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product Details anti-BRE Antibody Target Details BRE Application Details Handling back to top
Supplier Images
 image for anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibody (ABIN372906) anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibody
 image for anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibody (ABIN372906) anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibody (Image 2)