PREX2 Proteins

(DEP Domain Containing 2 (DEPDC2))

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase (By similarity).

Recommended next Filters:

All filter options

Would you like to try our new AI Search?

Show Filters

4 results

PREX2 Protein (AA 1-1606) (His tag)

custom-made DEPDC2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PREX2 Protein, UniprotID Q70Z35

3 images

Catalog No. ABIN7555072

Details

PREX2 Protein (AA 1-1598) (His tag)

custom-made DEPDC2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)