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Prothrombin Fragment 1+2,F1+2 Products

(Prothrombin Fragment 1+2 (F1+2))
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008].

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Featured Prothrombin Fragment 1+2,F1+2 Categories

Prothrombin Fragment 1+2,F1+2 Antibodies

High quality antibodies with extensive validation data.

Prothrombin Fragment 1+2,F1+2 ELISA Kits

Reliable ELISA kits for a wide range of species.

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Latest Publications for our Prothrombin Fragment 1+2,F1+2 products

Krenzlin, Gresser, Jussen, Riede, Taylor, Vogelaar, Ringel, Kempski, Alessandri: "The Cerebral Thrombin System Is Activated after Intracerebral Hemorrhage and Contributes to Secondary Lesion Growth and Poor Neurological Outcome in C57Bl/6 Mice." in: Journal of neurotrauma, Vol. 37, Issue 12, pp. 1481-1490, (2020) (PubMed).

Jing, Hu, Li, Wang, Si, Zheng, Liu, Liao, Liao, Bin: "Assessment of Thrombotic Risk in Atrial Fibrillation with Ultrasound Molecular Imaging of P-Selectin." in: Thrombosis and haemostasis, Vol. 118, Issue 2, pp. 388-400, (2019) (PubMed).

Chansai, Fucharoen, Fucharoen, Jetsrisuparb, Chumpia: "Elevations of Thrombotic Biomarkers in Hemoglobin H Disease." in: Acta haematologica, Vol. 139, Issue 1, pp. 47-51, (2019) (PubMed).

Mitrosz, Kazimierczyk, Sobkowicz, Waszkiewicz, Kralisz, Frank, Piszcz, Galar, Dobrzycki, Musial, Hirnle, Kaminski, Tycinska: "The causes of thrombocytopenia after transcatheter aortic valve implantation." in: Thrombosis research, Vol. 156, pp. 39-44, (2018) (PubMed).

Mitrosz, Kazimierczyk, Chlabicz, Sobkowicz, Waszkiewicz, Lisowska, Dobrzycki, Musial, Hirnle, Kaminski, Tycinska: "Perioperative thrombocytopenia predicts poor outcome in patients undergoing transcatheter aortic valve implantation." in: Advances in medical sciences, Vol. 63, Issue 1, pp. 179-184, (2018) (PubMed).

Shaya, Saldanha, Vaezzadeh, Zhou, Ni, Gross: "Comparison of the effect of dabigatran and dalteparin on thrombus stability in a murine model of venous thromboembolism." in: Journal of thrombosis and haemostasis : JTH, Vol. 14, Issue 1, pp. 143-52, (2016) (PubMed).

Teligui, Dalmayrac, Corbeau, Bouquet, Godon, Denommé, Binuani, Verron, Boer, Baufreton: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." in: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).

Nishank, Singh, Yadav: "Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India." in: European journal of haematology, Vol. 91, Issue 5, pp. 462-6, (2014) (PubMed).

Teligui, Dalmayrac, Mabilleau, Macchi, Godon, Corbeau, Denommé, Bouquet, Boer, Baufreton: "An ex vivo evaluation of blood coagulation and thromboresistance of two extracorporeal circuit coatings with reduced and full heparin dose." in: Interactive cardiovascular and thoracic surgery, Vol. 18, Issue 6, pp. 763-9, (2014) (PubMed).

Johansson, Sørensen, Perner, Welling, Wanscher, Larsen, Ostrowski: "Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study." in: Critical care, Vol. 15, Issue 6, pp. R272, (2013) (PubMed).

Synonyms and alternative names related to Prothrombin Fragment 1+2,F1+2

coagulation factor II, thrombin (F2), coagulation factor II (F2), Cf-2, Cf2, FII, PT, RPRGL2, THPH1, thrombin

Protein level used designations for Prothrombin Fragment 1+2,F1+2

  • prepro-coagulation factor II
  • prothrombin
  • prothrombin B-chain
  • serine protease
  • coagulation factor 2
  • thrombin
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