ILK Protein (AA 1-452) (His tag)

Catalog No. ABIN1000949

Product Details

Target: ILK (Integrin-Linked Kinase (ILK))

Protein Type: Recombinant

Protein Characteristics: AA 1-452

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ILK protein is labelled with His tag.

Application: Western Blotting (WB), ELISA

Purpose: Integrin-Linked Kinase (ILK)

Sequence: MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MIVPILEKMQ DK

Characteristics: recombinant ILK1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK1 fulllength protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Purity: > 95 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 25 mM Sodium acetate pH 4.8, 50 % Glycerol

Storage: -20 °C

Storage Comment: Store at -20 °C

Target Details

Target: ILK (Integrin-Linked Kinase (ILK))

Alternative Name: Integrin-Linked Kinase (ILK Products)

Synonyms: CG10504 Protein, CT29478 Protein, DmILK Protein, Dmel\\CG10504 Protein, ILK Protein, ilk Protein, l(3)78Ca Protein, p59 Protein, AA511515 Protein, ESTM24 Protein, zgc:65842 Protein, ILK-1 Protein, ILK-2 Protein, P59 Protein, p59ILK Protein, Integrin linked kinase Protein, integrin linked kinase Protein, integrin linked kinase S homeolog Protein, integrin-linked protein kinase Protein, integrin-linked kinase Protein, Ilk Protein, ILK Protein, ilk.S Protein, CpipJ_CPIJ016644 Protein, Bm1_20815 Protein, Tsp_07213 Protein, Tsp_07224 Protein, Tsp_15354 Protein, ilk Protein

Background: Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage-independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies.,ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59, p59ILK.

Molecular Weight: 55.92 kDa

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration