ACVR2A Protein (AA 20-134) (His tag)
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- Target See all ACVR2A Proteins
- ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-134
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ACVR2A protein is labelled with His tag.
- Purpose
- Recombinant Human Activin Receptor 2A/Activin RIIA/ACVR2A (C-6His)
- Sequence
- AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPVDHHH HHH
- Characteristics
- Recombinant Human Activin Receptor Type-2A/ACVR2A is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Pro134) of Human ACVR2A fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ACVR2A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
- Abstract
- ACVR2A Products
- Synonyms
- ACVR2 Protein, ACVR2A Protein, XSTK9 Protein, actrii Protein, acvr2 Protein, ACTRII Protein, Acvr2 Protein, rActR-II Protein, actr2a Protein, acvr2a Protein, wu:fa02e10 Protein, ActrIIa Protein, TactrII Protein, activin A receptor type 2A Protein, activin A receptor type 2A L homeolog Protein, activin A receptor type 2Aa Protein, activin receptor IIA Protein, ACVR2A Protein, acvr2a Protein, Acvr2a Protein, acvr2a.L Protein, acvr2aa Protein
- Sub Type
- Fusionprotein
- Background
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Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Alternative Names: Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2 - Molecular Weight
- 14.35 kDa
- UniProt
- P27037
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