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CPB1 Protein (AA 16-417) (His tag)

CPB1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096227
  • Target See all CPB1 Proteins
    CPB1 (Carboxypeptidase B1 (Tissue) (CPB1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 16-417
    Origin
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CPB1 protein is labelled with His tag.
    Purpose
    Recombinant Human Carboxypeptidase B/CPB1 (C-6His)
    Sequence
    HHGGEHFEGE KVFRVNVEDE NHINIIRELA STTQIDFWKP DSVTQIKPHS TVDFRVKAED TVTVENVLKQ NELQYKVLIS NLRNVVEAQF DSRVRATGHS YEKYNKWETI EAWTQQVATE NPALISRSVI GTTFEGRAIY LLKVGKAGQN KPAIFMDCGF HAREWISPAF CQWFVREAVR TYGREIQVTE LLDKLDFYVL PVLNIDGYIY TWTKSRFWRK TRSTHTGSSC IGTDPNRNFD AGWCEIGASR NPCDETYCGP AAESEKETKA LADFIRNKLS SIKAYLTIHS YSQMMIYPYS YAYKLGENNA ELNALAKATV KELASLHGTK YTYGPGATTI YPAAGGSDDW AYDQGIRYSF TFELRDTGRY GFLLPESQIR ATCEETFLAI KYVASYVLEH LYVDHHHHHH
    Characteristics
    Recombinant Human Carboxypeptidase B/CPB1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (His16-Tyr417) of Human CPB1 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CPB1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CPB1 (Carboxypeptidase B1 (Tissue) (CPB1))
    Alternative Name
    cpb1 (CPB1 Products)
    Synonyms
    wu:fb60d07 Protein, wu:fb69b08 Protein, CPB1 Protein, pCPB Protein, CPB Protein, PASP Protein, PCPB Protein, Cpb Protein, 0910001A18Rik Protein, 1810063F02Rik Protein, 2210008M23Rik Protein, AI504870 Protein, carboxypeptidase B1 (tissue) Protein, carboxypeptidase B1 Protein, carboxypeptidase B1 S homeolog Protein, carboxypeptidase B Protein, cpb1 Protein, CPB1 Protein, cpb1.S Protein, CpipJ_CPIJ010799 Protein, CpipJ_CPIJ010801 Protein, VDBG_02663 Protein, LOC100562609 Protein, Cpb1 Protein
    Sub Type
    Fusionprotein
    Background
    Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.
    Alternative Names: Carboxypeptidase B, Pancreas-Specific Protein, PASP, CPB1, CPB, PCPB
    Molecular Weight
    46.94 kDa
    UniProt
    P15086
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