FABP3 Protein (AA 2-133) (His tag)
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- Target See all FABP3 Proteins
- FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-133
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FABP3 protein is labelled with His tag.
- Purpose
- Recombinant Human Fatty Acid-Binding Protein 3/FABP3/H-FABP (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA
- Characteristics
- Recombinant Human Fatty Acid-Binding Protein 3/FABP3 is produced with our E. coli expression system. The target protein is expressed with sequence (Val2-Ala133) of Human FABP3.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FABP3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 6.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
- Alternative Name
- fabp3 (FABP3 Products)
- Synonyms
- Fabph-1 Protein, Fabph-4 Protein, Fabph1 Protein, Fabph4 Protein, H-FABP Protein, Mdgi Protein, FABP11 Protein, M-FABP Protein, MDGI Protein, O-FABP Protein, FABP Protein, FABP-3 Protein, fabp3 Protein, fatty acid binding protein 3 Protein, fatty acid binding protein 3, muscle and heart Protein, FABP3 Protein, Fabp3 Protein, fabp3 Protein
- Background
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Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.
Alternative Names: Fatty Acid-Binding Protein Heart, Fatty Acid-Binding Protein 3, Heart-Type Fatty Acid-Binding Protein, H-FABP, Mammary-Derived Growth Inhibitor, MDGI Muscle Fatty Acid-Binding Protein, M-FABP, FABP3, FABP11, MDGI - Molecular Weight
- 17.02 kDa
- UniProt
- P05413
- Pathways
- Monocarboxylic Acid Catabolic Process
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