FGFRL1 Protein (AA 25-378) (His tag)

Catalog No. ABIN1096660

Product Details

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Protein Type: Recombinant

Protein Characteristics: AA 25-378

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This FGFRL1 protein is labelled with His tag.

Purpose: Recombinant Human FGF R5/FGFRL1 (C-6His)

Sequence: ARGPPKMADK VVPRQVARLG RTVRLQCPVE GDPPPLTMWT KDGRTIHSGW SRFRVLPQGL KVKQVEREDA GVYVCKATNG FGSLSVNYTL VVLDDISPGK ESLGPDSSSG GQEDPASQQW ARPRFTQPSK MRRRVIARPV GSSVRLKCVA SGHPRPDITW MKDDQALTRP EAAEPRKKKW TLSLKNLRPE DSGKYTCRVS NRAGAINATY KVDVIQRTRS KPVLTGTHPV NTTVDFGGTT SFQCKVRSDV KPVIQWLKRV EYGAEGRHNS TIDVGGQKFV VLPTGDVWSR PDGSYLNKLL ITRARQDDAG MYICLGANTM GYSFRSAFLT VLPDPKPPGP PVASSSSATS LPWPVDHHHH HH

Characteristics: Recombinant Human Fibroblast Growth Factor Receptor-Like 1/FGFRL1 produced by transfected human cells is a secreted protein with sequence (Ala25-Pro378) of Human FGFRL1 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Alternative Name: fgfrl1 (FGFRL1 Products)

Synonyms: fgfrl1 Protein, zgc:64084 Protein, FGFR5 Protein, FGFR5beta Protein, FGFR5gamma Protein, Fgfr5 Protein, FHFR Protein, XFGFRL1 Protein, Xndk Protein, fgfrl1-a Protein, fgfrl1-b Protein, ndk Protein, im:7154242 Protein, fibroblast growth factor receptor like 1a Protein, fibroblast growth factor receptor-like 1 Protein, fibroblast growth factor receptor like 1 Protein, fibroblast growth factor receptor like 1 L homeolog Protein, fibroblast growth factor receptor like 1b Protein, fgfrl1a Protein, Fgfrl1 Protein, FGFRL1 Protein, fgfrl1.L Protein, fgfrl1b Protein

Sub Type: Fusionprotein

Background: Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.
Alternative Names: Fibroblast Growth Factor Receptor-Like 1, FGF Receptor-Like Protein 1, FGF Homologous Factor Receptor, FGFR-Like Protein, Fibroblast Growth Factor Receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR

Molecular Weight: 39.9 kDa

UniProt: Q8N441

Pathways: RTK Signaling