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MBIP Protein (AA 1-344) (His tag)

MBIP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1097134
  • Target See all MBIP Proteins
    MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-344
    Origin
    • 6
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MBIP protein is labelled with His tag.
    Purpose
    Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIPP (N-6His)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MAAATEHNRP SSGDRNLERR CSPNLSREVL YEIFRSLHTL VGQLDLRDDV VKITIDWNKL QSLSAFQPAL LFSALEQHIL YLQPFLAKLQ SPIKEENTTA VEEIGRTEMG NKNEVNDKFS IGDLQEEEKH KESDLRDVKK TQIHFDPEVV QIKAGKAEID RRISAFIERK QAEINENNVR EFCNVIDCNQ ENSCARTDAI FTPYPGFKSH VKVSRVVYTY GPQTRPEGIP GSGHKPNSML RDCGNQAVEE RLQNIEAHLR LQTGGPVPRD IYQRIKKLED KILELEGISP EYFQSVSFSG KRRKVQPPQQ NYSLAELDEK ISALKQALLR KSREAESMAT HHLPLEHHHH HH
    Characteristics
    Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIP is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Pro344) of Human MBIP fused with a His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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    Discover our top product MBIP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
    Alternative Name
    MBIP (MBIP Products)
    Synonyms
    4933408E06Rik Protein, MAP3K12 binding inhibitory protein 1 Protein, Mbip Protein, mbip Protein, MBIP Protein
    Sub Type
    Fusionprotein
    Background
    MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.
    Alternative Names: MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP
    Molecular Weight
    42.51 kDa
    UniProt
    Q9NS73
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