SENP7 Protein (AA 695-864) (His tag)
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- Target See all SENP7 Proteins
- SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 695-864
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SENP7 protein is labelled with His tag.
- Purpose
- Recombinant Human Sentrin-Specific Protease 7/SENP7 (N-6His)
- Sequence
- MKLKSVSQPS NTDAAKPTYT FLQKQSSGCY SLSITSNPDE EWREVRHTGL VQKLIVYPPP PTKGGLGVTN EDLECLEEGE FLNDVIIDFY LKYLILEKAS DELVERSHIF SSFFYKCLTR KENNLTEDNP NLSMAQRRHK RVRTWTRHIN IFNKDYIFVP VNESSHWYLA
- Characteristics
- Recombinant Human Sentrin-Specific Protease 7/SENP7 is produced by our E. coli expression system. The target protein is expressed with sequence (Met695-Ala864) of Human SENP7.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SENP7 Protein
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SUMO1/sentrin Specific Protease 7 (SENP7) (AA 1-110) protein (GST tag)
SENP7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SUMO1/sentrin Specific Protease 7 (SENP7) (AA 1-1050) protein (Strep Tag)Crystallography grade SENP7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
SUMO1/sentrin Specific Protease 7 (SENP7) (AA 1-1037) protein (Strep Tag)Crystallography grade SENP7 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
SUMO1/sentrin Specific Protease 7 (SENP7) (Transcript Variant 2) protein (His tag)SENP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 5 % Glycerol, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SENP7 (SUMO1/sentrin Specific Protease 7 (SENP7))
- Alternative Name
- Sentrin-Specific Protease 7/SENP7 (SENP7 Products)
- Synonyms
- SENP7 Protein, 2410152H17Rik Protein, 2810413I22Rik Protein, 2900036C23Rik Protein, 6030449K19Rik Protein, AI790676 Protein, mKIAA1707 Protein, SUMO1/sentrin specific peptidase 7 Protein, SENP7 Protein, Senp7 Protein
- Background
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Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
Alternative Names: Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2 - Molecular Weight
- 27.3 kDa
- UniProt
- Q9BQF6
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