UROS Protein (AA 1-265) (His tag)
-
- Target See all UROS Proteins
- UROS (Uroporphyrinogen III Synthase (UROS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-265
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UROS protein is labelled with His tag.
- Purpose
- Recombinant Human Uroporphyrinogen-III Synthase/UROIIIS (C-6His)
- Sequence
- MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCCLEHHH HHH
- Characteristics
- Recombinant Human Uroporphyrinogen-III Synthase/UROIIIS is produced by our E.coli expression system. The target protein is expressed with sequence (Met1-Cys265) of Human UROS fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product UROS Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 10 % Glycerol, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
-
- Target
- UROS (Uroporphyrinogen III Synthase (UROS))
- Alternative Name
- UROIIIS (UROS Products)
- Synonyms
- wu:fd13d11 Protein, zgc:110240 Protein, UROIIIS Protein, Afu6g12800 Protein, UROS Protein, MGC85561 Protein, AI415298 Protein, Uros3 Protein, ARABIDOPSIS THALIANA UROPORPHYRINOGEN III SYNTHASE Protein, ATDUF3 Protein, ATUROS Protein, DOMAIN OF UNKNOWN FUNCTION 724 3 Protein, DUF3 Protein, T9J22.21 Protein, T9J22_21 Protein, UROPORPHYRINOGEN III SYNTHASE Protein, uroporphyrinogen III synthase Protein, uroporphyrinogen-III synthase (UroS) Protein, uroporphyrinogen-iii synthase Protein, uroporphyrinogen III synthase L homeolog Protein, uroporphyrinogen-III synthase family protein Protein, uros Protein, UROS Protein, AFUA_6G12800 Protein, UroS Protein, uros.L Protein, Uros Protein, HEMD Protein
- Sub Type
- Fusionprotein
- Background
-
Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
Alternative Names: Uroporphyrinogen-III Synthase, UROIIIS, UROS, Hydroxymethylbilane Hydrolyase [Cyclizing], Uroporphyrinogen-III Cosynthase, UROS - Molecular Weight
- 29.7 kDa
- UniProt
- P10746
-