VSIG2 Protein (AA 24-243) (His tag)
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- Target See all VSIG2 Proteins
- VSIG2 (V-Set and Immunoglobulin Domain Containing 2 (VSIG2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-243
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This VSIG2 protein is labelled with His tag.
- Purpose
- Recombinant Human V-Set and Ig Domain-Containing Protein 2/VSIG2 (C-6His)
- Sequence
- VEVKVPTEPL STPLGKTAEL TCTYSTSVGD SFALEWSFVQ PGKPISESHP ILYFTNGHLY PTGSKSKRVS LLQNPPTVGV ATLKLTDVHP SDTGTYLCQV NNPPDFYTNG LGLINLTVLV PPSNPLCSQS GQTSVGGSTA LRCSSSEGAP KPVYNWVRLG TFPTPSPGSM VQDEVSGQLI LTNLSLTSSG TYRCVATNQM GSASCELTLS VTEPSQGRVA VDHHHHHH
- Characteristics
- Recombinant Human V-Set and Immunoglobulin Domain-Containing Protein 2/VSIG2 produced by transfected human cells is a secreted protein with sequence (Val24-Ala243) of Human VSIG2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- VSIG2 (V-Set and Immunoglobulin Domain Containing 2 (VSIG2))
- Alternative Name
- vsig2 (VSIG2 Products)
- Synonyms
- 2210413P10Rik Protein, CTH Protein, CTXL Protein, 1190004B15Rik Protein, AU040484 Protein, CTX Protein, Ctm Protein, V-set and immunoglobulin domain containing 2 Protein, VSIG2 Protein, Vsig2 Protein
- Sub Type
- Fusionprotein
- Background
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V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains, in several T-cell receptors such as CD2 (Cluster of Differentiation 2), CD4, CD80, and CD86, in myelin membrane adhesion molecules, in junction adhesion molecules (JAM), in tyrosine-protein kinase receptors, and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot, and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.
Alternative Names: V-Set and Immunoglobulin Domain-Containing Protein 2, Cortical Thymocyte-Like Protein, CT-Like Protein, VSIG2, CTH, CTXL - Molecular Weight
- 24.2 kDa
- UniProt
- Q96IQ7
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