RANBP1 Protein (His tag)
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- Target See all RANBP1 Proteins
- RANBP1 (RAN Binding Protein 1 (RANBP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RANBP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product RANBP1 Protein
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- Comment
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Synonyms: RAN binding protein 1, HTF9A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT, 10% glycerol, 0.1 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- RANBP1 (RAN Binding Protein 1 (RANBP1))
- Alternative Name
- RANBP1 (RANBP1 Products)
- Synonyms
- MGC64314 Protein, zeh1094 Protein, zgc:85649 Protein, hm:zeh1094 Protein, wu:fa96a09 Protein, wu:fj39g07 Protein, HTF9A Protein, Htf9a Protein, RAN binding protein 1 S homeolog Protein, RAN binding protein 1 L homeolog Protein, ran binding protein 1 Protein, RAN binding protein 1 Protein, ran-specific GTPase-activating protein pseudogene Protein, ranbp1.S Protein, ranbp1.L Protein, PVX_090070 Protein, GL50803_16969 Protein, LOC100343953 Protein, ranbp1 Protein, RANBP1 Protein, Ranbp1 Protein
- Background
- RAN binding protein 1, also known as RANBP1, belongs to a family of proteins that bind Ran GTPase which is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). Also, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Recombinant human RANBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25.8 kDa (225aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- NCBI Accession
- NP_002873
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