CKMT1A Protein (His tag)
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- Target See all CKMT1A Proteins
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CKMT1A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CKMT1A Protein
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Creatine Kinase, Mitochondrial 1A (CKMT1A) protein (His tag)
CKMT1A Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 40-417) protein (His tag)CKMT1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Comment
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Synonyms: Creatine kinase U-type, mitochondrial, CKMT1, CKMT1B, UMTCK
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Alternative Name
- CKMT1A (CKMT1A Products)
- Synonyms
- CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein
- Background
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Recombinant human CKMT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 45 kDa (403aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001015001
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