GPN1 Protein (His tag)
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- Target See all GPN1 Proteins
- GPN1 (GPN-Loop GTPase 1 (GPN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GPN1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product GPN1 Protein
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- Comment
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Synonyms: XPA binding protein 1, GTPase, GPN1, ATPBD1A, MBDIN, NTPBP
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- GPN1 (GPN-Loop GTPase 1 (GPN1))
- Alternative Name
- XAB1 (GPN1 Products)
- Synonyms
- ATPBD1A Protein, MBDIN Protein, NTPBP Protein, RPAP4 Protein, XAB1 Protein, GPN1 Protein, MGC137872 Protein, 2410004J02Rik Protein, AI449615 Protein, Xab1 Protein, GPN-loop GTPase 1 Protein, GPN1 Protein, Gpn1 Protein
- Background
- XAB1, as known as GPN1, belongs to the GPN-loop GTPase family. Small GTPases share a biochemical mechanism and act as binary molecular switches. One important function of small GTPases in the cell is nucleocytoplasmic transport of both proteins and RNA. This protein may play a role in DNA repair and may function in activation of transcription. And it forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Recombinant human XAB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 44.3kDa (398aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_009197
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