Asialoglycoprotein Receptor 2 Protein (ASGR2) (His tag)
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- Target See all Asialoglycoprotein Receptor 2 (ASGR2) Proteins
- Asialoglycoprotein Receptor 2 (ASGR2)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Asialoglycoprotein Receptor 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ASGR2 Protein
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- Comment
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Synonyms: Asialoglycoprotein receptor 2, ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Asialoglycoprotein Receptor 2 (ASGR2)
- Alternative Name
- ASGR2 (ASGR2 Products)
- Synonyms
- ASGR2 Protein, asgr2 Protein, MGC137129 Protein, ASGP-R2 Protein, ASGPR2 Protein, CLEC4H2 Protein, HBXBP Protein, HL-2 Protein, Asgr Protein, Asgr-2 Protein, asialoglycoprotein receptor 2 Protein, C-type lectin domain family 10 member A Protein, ASGR2 Protein, clec10a Protein, Asgr2 Protein, LOC100347178 Protein
- Background
- ASGR2 is a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. It may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2 is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human ASGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 28.9 kDa (255aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001172
- Pathways
- Thyroid Hormone Synthesis
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