Sdhaf2 Protein (His tag)
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- Target See all Sdhaf2 Proteins
- Sdhaf2 (Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Sdhaf2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product Sdhaf2 Protein
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- Comment
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Synonyms: Succinate dehydrogenase assembly factor 2, mitochondrial, C11orf79, PGL2, SDH5
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Sdhaf2 (Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2))
- Alternative Name
- SDHAF2 (Sdhaf2 Products)
- Synonyms
- C14H11orf79 Protein, C11orf79 Protein, PGL2 Protein, SDH5 Protein, 0610038F07Rik Protein, AA407634 Protein, AW049997 Protein, RGD1309216 Protein, wu:fj30e04 Protein, zgc:163000 Protein, succinate dehydrogenase complex assembly factor 2 Protein, SDHAF2 Protein, Sdhaf2 Protein, sdhaf2 Protein
- Background
- SDHAF2 is a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Defects in SDHAF2 are the cause of hereditary paragangliomas type 2 (PGL2), also known as familial non-chromaffin paragangliomas type 2. Paragangliomas refer to rare and mostly benign tumors that arise from any component of the neuroendocrine system. Recombinant human SDHAF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 19.0kDa (160aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_060311
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