PIP4K2B Protein (His tag)
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- Target See all PIP4K2B Proteins
- PIP4K2B (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, beta (PIP4K2B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIP4K2B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
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- Comment
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Synonyms: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PIP4K2B (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, beta (PIP4K2B))
- Alternative Name
- PIP4K2B (PIP4K2B Products)
- Synonyms
- PIP5K2B Protein, si:ch211-279l9.5 Protein, PI5P4KB Protein, PIP5KIIB Protein, PIP5KIIbeta Protein, AI848124 Protein, PI5P4Kbeta Protein, Pip5k2b Protein, c11 Protein, phosphatidylinositol-5-phosphate 4-kinase type 2 beta Protein, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b Protein, phosphatidylinositol-5-phosphate 4-kinase, type II, beta Protein, PIP4K2B Protein, pip4k2ab Protein, pip4k2b Protein, Pip4k2b Protein
- Background
- PIP4K2B catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. It is a member of the phosphatidylinositol-4-phosphate 5-kinase family. The amino acid sequence of PIP4K2B does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, PIP4K2B interacts with p55 TNF receptor. Recombinant human PIP4K2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.8 kDa (439aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_003550
- Pathways
- Inositol Metabolic Process
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