AIDA Protein (His tag)
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- Target See all AIDA Proteins
- AIDA (Axin Interactor, Dorsalization Associated (AIDA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AIDA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product AIDA Protein
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- Comment
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Synonyms: Axin interactor, dorsalization-associated, C1orf80, RP11-378J18.7
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.2 M NaCl,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- AIDA (Axin Interactor, Dorsalization Associated (AIDA))
- Alternative Name
- AIDA (AIDA Products)
- Synonyms
- C1orf80 Protein, RP11-378J18.7 Protein, 2610208M17Rik Protein, BC004835 Protein, zgc:73327 Protein, AIDA Protein, axin interactor, dorsalization associated Protein, axin interactor, dorsalization associated L homeolog Protein, axin interactor, dorsalization associated S homeolog Protein, AIDA Protein, Aida Protein, aida Protein, aida.L Protein, aida.S Protein
- Background
- AIDA acts as a ventralizing factor during embryogenesis. This protein inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. Recombinant human AIDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 37.4kDa(329aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_073742
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