EYA2 Protein (His tag)
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- Target See all EYA2 Proteins
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EYA2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EYA2 Protein
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Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 244-514) protein (His tag)
EYA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 1-538) protein (GST tag)EYA2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 1-514), (Isoform 2) protein (His-SUMO Tag)EYA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Comment
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Synonyms: Eyes absent homolog 2, EAB1, MGC10614
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15 M NaCl, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
- Alternative Name
- EYA2 (EYA2 Products)
- Synonyms
- EYA2 Protein, zgc:92279 Protein, eab1 Protein, Eab1 Protein, EAB1 Protein, EYA transcriptional coactivator and phosphatase 2 Protein, EYA2 Protein, eya2 Protein, Eya2 Protein
- Background
- EYA2, also known as eyes absent homolog 2, is a member of tyrosine phosphatase family that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). This protein promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Recombinant human EYA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 33.2 kDa (295aa), confirmed by MALDI-TOF
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