HBa2 Protein (His tag)

Catalog No. ABIN1098667

Product Details

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HBa2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Hemoglobin subunit alpha, nucleophosmin/nucleoplasmin 2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol, 2 M Urea, 2 mM DTT

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Alternative Name: HBA2 (HBa2 Products)

Synonyms: HBAM Protein, Hba-a1 Protein, Hba-a2 Protein, hba2 Protein, HBH Protein, hba5 Protein, HBA2 Protein, alpha globin Protein, HBA1 Protein, HBAI Protein, HBAII Protein, Glnc1 Protein, GloA Protein, hemoglobin, alpha 1 Protein, hemoglobin subunit alpha 1 S homeolog Protein, hemoglobin subunit alpha 2 Protein, hemoglobin subunit alpha 2 L homeolog Protein, hemoglobin subunit mu Protein, hemoglobin, alpha 2 Protein, hemoglobin subunit alpha-2-like Protein, hemoglobin alpha, adult chain 1 Protein, hemoglobin alpha, adult chain 2 Protein, Hba1 Protein, hba1.S Protein, HBA2 Protein, hba2.L Protein, HBM Protein, HBA Protein, Hba2 Protein, LOC102168959 Protein, Hba-a1 Protein, Hba-a2 Protein

Background: Hemoglobin subunit alpha, also known as HBA2, belongs to the globin family. HBA2 is involved in oxygen transport from the lung to the various peripheral tissues. The alpha-2(HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported. Recombinant human HBA2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 19.5 kDa (179aa)

NCBI Accession: NP_000508