RASSF1 Protein (His tag)
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- Target See all RASSF1 Proteins
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RASSF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
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- Comment
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Synonyms: Ras association domain-containing protein 1, 123F2, NORE2A, RASSF1, RDA32, REH3P21
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Alternative Name
- RASSF1A (RASSF1 Products)
- Synonyms
- RASSF1 Protein, zgc:92505 Protein, wu:fc17f02 Protein, zgc:112224 Protein, 123F2 Protein, NORE2A Protein, RASSF1A Protein, RDA32 Protein, REH3P21 Protein, AA536941 Protein, AU044980 Protein, Rassf1A Protein, Rassf1B Protein, Rassf1C Protein, NPR2-like, GATOR1 complex subunit Protein, Ras association (RalGDS/AF-6) domain family 1 Protein, Ras association domain family member 1 Protein, putative rassf1 Protein, Ras association domain family member 1 L homeolog Protein, Ras association (RalGDS/AF-6) domain family member 1 Protein, NPRL2 Protein, rassf1 Protein, RASSF1 Protein, Smp_157340 Protein, rassf1.L Protein, Rassf1 Protein
- Background
- RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. Recombinant human RASSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 42.9 kDa (376aa)
- NCBI Accession
- NP_009113
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