SGCD Protein (His tag)
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- Target See all SGCD Proteins
- SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SGCD protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SGCD Protein
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- Comment
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Synonyms: Delta-sarcoglycan, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SGCD (Sarcoglycan, delta (35kDa Dystrophin-Associated Glycoprotein) (SGCD))
- Alternative Name
- SGCD (SGCD Products)
- Synonyms
- BEST:GH21860 Protein, CG14808 Protein, CT34621 Protein, DmSCG-gammadelta Protein, Dmel\\CG14808 Protein, EG:4F1.1 Protein, GH21860 Protein, Sgcd Protein, wu:fc49e11 Protein, zgc:110649 Protein, 35DAG Protein, CMD1L Protein, DAGD Protein, SG-delta Protein, SGCDP Protein, SGD Protein, Delta-SG Protein, 35kDa Protein, delta-SG Protein, sarcoglycan delta Protein, Sarcoglycan delta Protein, sarcoglycan, delta (dystrophin-associated glycoprotein) Protein, sarcoglycan, delta Protein, SGCD Protein, Scgdelta Protein, sgcd Protein, Sgcd Protein
- Background
- SGCD is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. The mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed. In melanocytic cells SGCD gene expression may be regulated by MITF. Recombinant human SGCD protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 28 kDa (257aa)
- NCBI Accession
- NP_001121681
- Pathways
- Maintenance of Protein Location
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