RECQL2 Protein (AA 1322-1432) (GST tag)

Catalog No. ABIN1325380

Product Details

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Protein Type: Recombinant

Protein Characteristics: AA 1322-1432

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This RECQL2 protein is labelled with GST tag.

Application: ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)

Purpose: WRN (Human) Recombinant Protein (Q01)

Sequence: NPPVNSDMSK ISLIRMLAPE NIDTYLIHMA IEILKHGPDS GLQPSCDVNK RRCFPGSEEI CSSSKRSKEE VGINTETSSA ERKRRLPVWF AKGSDTSKKL MDKTKRGGLF S

Characteristics: Human WRN partial ORF ( NP_000544, 1322 a.a. - 1432 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Sadahira, Sugihara, Fujiwara, Nishimura, Suetsugu, Takeshita, Okamura, Goto: "WRN protein as a novel erythroblast immunohistochemical marker with applications for the diagnosis of Werner syndrome." in: Virchows Archiv : an international journal of pathology, Vol. 466, Issue 3, pp. 343-50, (2015) (PubMed).

Target Details

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Alternative Name: WRN (WRN Products)

Synonyms: RECQ3 Protein, RECQL2 Protein, RECQL3 Protein, xBLM Protein, recq2 Protein, recql2 Protein, recql3 Protein, AI846146 Protein, ffa-1 Protein, xwrn Protein, RGD1564788 Protein, Werner syndrome RecQ like helicase Protein, mediator of RNA polymerase II transcription subunit 34 Protein, Bloom syndrome RecQ like helicase Protein, Werner syndrome, RecQ helicase-like L homeolog Protein, WRN Protein, LOC9327212 Protein, blm Protein, Wrn Protein, wrn.L Protein

Background: Gene: Werner syndrome
Synonyms: DKFZp686C2056, RECQ3, RECQL2, RECQL3

Gene ID: 7486

NCBI Accession: NM_000553

Pathways: DNA Damage Repair