IL1R1 Protein (AA 21-336) (Fc Tag)
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- Target See all IL1R1 Proteins
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-336
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL1R1 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to human IL-1beta.
- Cross-Reactivity
- Human
- Characteristics
- Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1R1 Protein
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Interleukin 1 Receptor, Type I (IL1R1) (AA 20-338) protein (His tag)
IL1R1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type I (IL1R1) (AA 18-332) protein (His tag)IL1R1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type I (IL1R1) protein (Fc Tag)IL1R1 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Interleukin 1 Receptor, Type I (IL1R1) (AA 19-328) proteinIL1R1 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Interleukin 1 Receptor, Type I (IL1R1) (AA 18-127) protein (GST tag)IL1R1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (Fc Tag)IL1R1 Origin: Mouse Host: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag,Fc Tag)IL1R1 Origin: Rat Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag)IL1R1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag)IL1R1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Blocks IL-1beta activity.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Abstract
- IL1R1 Products
- Synonyms
- CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
- Background
- IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
- Molecular Weight
- ~80kDa (SDS-PAGE)
- UniProt
- P14778
- Pathways
- NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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