CD137 Protein (AA 1-185, Extracellular Domain) (Fc Tag)
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- Target See all CD137 (TNFRSF9) Proteins
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular Domain, AA 1-185
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD137 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- The extracellular domain of mouse CD137 (aa 1-185) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF9 Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (Fc-Avi Tag)
TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His tag)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His-Avi Tag,Biotin)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His tag)TNFRSF9 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (Fc-Avi Tag,Biotin)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-211) protein (His tag)TNFRSF9 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) protein (mFc-His Tag)TNFRSF9 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 46-128) protein (His-DYKDDDDK-Strep II Tag)TNFRSF9 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-186) protein (His-DYKDDDDK-Strep II Tag)TNFRSF9 Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (AA 24-211) protein (Fc Tag)TNFRSF9 Origin: Mouse Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm filtered solution in PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Alternative Name
- CD137 (TNFRSF9 Products)
- Synonyms
- TNFRSF9 Protein, zgc:136557 Protein, 4-1BB Protein, CD137 Protein, CDw137 Protein, ILA Protein, A930040I11Rik Protein, AA408498 Protein, AI325004 Protein, Cd137 Protein, Ly63 Protein, tumor necrosis factor receptor superfamily member 9 Protein, TNF receptor superfamily member 9 Protein, tumor necrosis factor receptor superfamily, member 9a Protein, tumor necrosis factor receptor superfamily, member 9 Protein, TNFRSF9 Protein, tnfrsf9a Protein, Tnfrsf9 Protein
- Background
- CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
- Molecular Weight
- ~50kDa (SDS-PAGE)
- UniProt
- P20334
- Pathways
- Cancer Immune Checkpoints
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