CTRP5 Protein (AA 16-243) (His tag)
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- Target See all CTRP5 (C1QTNF5) Proteins
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-243
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CTRP5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human CTRP5 (aa 16-243) is fused at the N-terminus to a His-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product C1QTNF5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in distilled water.
- Concentration
- Lot specific
- Buffer
- Lyophilized from a 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
- Alternative Name
- CTRP5 (C1QTNF5 Products)
- Synonyms
- C1QTNF5 Protein, wu:fb02c10 Protein, wu:fb02f05 Protein, zgc:112378 Protein, CTRP5 Protein, Ctrp5 Protein, C1q and tumor necrosis factor related protein 5 Protein, C1q and TNF related 5 Protein, C1QTNF5 Protein, c1qtnf5 Protein, C1qtnf5 Protein
- Background
- CTRP5 (C1qTNF-related protein 5, C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).
- Molecular Weight
- ~26kDa (SDS-PAGE)
- UniProt
- Q9BXJ0
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