GPX3 Protein (AA 21-226) (DYKDDDDK Tag)
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- Target See all GPX3 Proteins
- GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-226
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GPX3 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human GPX3 (aa 21-226) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product GPX3 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.2.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
- Alternative Name
- GPX3 (GPX3 Products)
- Synonyms
- GPX3 Protein, DKFZp469D1932 Protein, AA960521 Protein, EGPx Protein, GPx Protein, GSHPx-3 Protein, GSHPx-P Protein, GPx-3 Protein, GPx-P Protein, Gpxp Protein, glutathione peroxidase 3 Protein, gpx3 Protein, GPX3 Protein, Gpx3 Protein
- Background
- Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
- Molecular Weight
- ~30kDa (SDS-PAGE)
- UniProt
- P22352
- Pathways
- Thyroid Hormone Synthesis
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