FASL Protein (AA 103-281, Extracellular Domain, Soluble) (DYKDDDDK Tag)
-
- Target See all FASL Proteins
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Soluble, Extracellular Domain, AA 103-281
-
Origin
- Human, Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FASL protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human, Mouse (Murine)
- Characteristics
- The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.05EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FASL Protein
-
Fas Ligand (TNF Superfamily, Member 6) (FASL) protein (His tag)
FASL Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 134-281) (Active) protein (His tag)FASL Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (GST tag)FASL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 172-281) protein (GST tag)FASL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 101-279) protein (His tag)Crystallography grade FASL Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-281) protein (Strep Tag)Crystallography grade FASL Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-279) protein (Strep Tag)Crystallography grade FASL Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-81) protein (rho-1D4 tag)Crystallography grade FASL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 130-281) protein (rho-1D4 tag)Crystallography grade FASL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fas Ligand (TNF Superfamily, Member 6) (FASL) (AA 1-129) protein (rho-1D4 tag)Crystallography grade FASL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1μg/ml TNF Ligands Enhancer (Prod. No. AG-35B-0001). In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
-
- Target
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Alternative Name
- FasL (FASL Products)
- Synonyms
- ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
- Background
- FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
- Molecular Weight
- ~33kDa (SDS-PAGE)
- UniProt
- P48023
- Pathways
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
-
