ARHGEF7 Protein (AA 1-646) (His tag)

Catalog No. ABIN1475722

Product Details

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Protein Type: Recombinant

Protein Characteristics: AA 1-646

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This ARHGEF7 protein is labelled with His tag.

Application: ELISA

Sequence: MTDNANSQLV VRAKFNFQQT NEDELSFSKG DVIHVTRVEE GGWWEGTHNG RTGWFPSNYV REIKPSEKPV SPKSGTLKSP PKGFDTTAIN KSYYNVVLQN ILETEHEYSK ELQSVLSTYL WPLQTSEKLS SANTSYLMGN LEEISSFQQV LVQSLEECTK SPEAQQRVGG CFLSLMPQMR TLYLAYCANH PSAVSVLTEH SEDLGEFMET KGASSPGILV LTTGLSKPFM RLDKYPTLLK ELERHMEDYH PDRQDIQKSM TAFKNLSAQC QEVRKRKELE LQILTEPIRS WEGDDIKTLG SVTYMSQVTI QCAGSEEKNE RYLLLFPNLL LMLSASPRMS GFIYQGKLPT TGMTITKLED SENHRNAFEI SGSMIERILV SCNNQQDLHE WVEHLQRQTK VTSVSNPTIK PHSVPSHTLP SHPLTPSSKH ADSKPVALTP AYHTLPHPSH HGTPHTTISW GPLEPPKTPK PWSLSCLRPA PPLRPSAALC YKEDLSRSPK TMKKLLPKRK PERKPSDEEF AVRKSTAALE EDAQILKVIE AYCTSAKTRQ TLNSSSRKES APQVLLPEEE KIIVEETKSN GQTVIEEKSL VDTVYALKDE VQELRQDNKK MKKSLEEEQR ARKDLEKLVR KVLKNMNDPA WDETNL

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Alternative Name: Rho guanine nucleotide exchange factor 7 (Arhgef7) (ARHGEF7 Products)

Synonyms: BETA-PIX Protein, COOL-1 Protein, COOL1 Protein, Nbla10314 Protein, P50 Protein, P50BP Protein, P85 Protein, P85COOL1 Protein, P85SPR Protein, PAK3 Protein, PIXB Protein, cool1 Protein, p50 Protein, p85 Protein, pak3 Protein, pixb Protein, ARHGEF7 Protein, P85spr Protein, Pak3bp Protein, Cool Protein, PIX Protein, betaPix Protein, betaPix-b Protein, betaPix-c Protein, cool-1 Protein, mKIAA0142 Protein, p85Cool1 Protein, p85SPR Protein, arhgef7 Protein, bbh Protein, bpix Protein, im:7142367 Protein, wu:fc35h08 Protein, zgc:101775 Protein, Rho guanine nucleotide exchange factor 7 Protein, Rho guanine nucleotide exchange factor 7 S homeolog Protein, ankyrin repeat domain 10 Protein, Rho guanine nucleotide exchange factor (GEF7) Protein, Rho guanine nucleotide exchange factor (GEF) 7b Protein, ARHGEF7 Protein, arhgef7.S Protein, arhgef7 Protein, ANKRD10 Protein, Arhgef7 Protein, arhgef7b Protein

Background: Recommended name: Rho guanine nucleotide exchange factor 7.
Alternative name(s): Beta-Pix PAK-interacting exchange factor beta

UniProt: O55043

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation