EIF2AK1 Protein (AA 1-620) (His tag)

Catalog No. ABIN1612582

Product Details

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Protein Type: Recombinant

Protein Characteristics: AA 1-620

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This EIF2AK1 protein is labelled with His tag.

Application: ELISA

Sequence: MLGGGSVDGE RDTDDDAAGA VAAPPAIDFP AEVSDPKYDE SDVPAELQVF KEPLQQPTFP FLVANQLLLV SLLEHLSHVH EPNPLHSKQV FKLLCQTFIK MGLLSSFTCS DEFSSLRLHH NRAITHLMRS AKERVRQDPC QDNSYMQKIR SREIALEAQT SRYLNEFEEL AILGKGGYGR VYKVRNKLDG QHYAIKKILI KSATKTDCMK VLREVKVLAG LQHPNIVGYH TAWIEHVHVL QPQDRVPIQL PSLEVLSEHE GDRNQGGVKD NESSSSIIFA ELTPEKENPL AESDVKNENN NLVSYRANLV IRSSSESESS IELQEDGLNE SPLRPVVKHQ LPLGHSSDVE GNFTSTDESS EDNLNLLGQT EARYHLMLHI QMQLCELSLW DWIAERNNRS RECVDEAACP YVMASVATKI FQELVEGVFY IHNMGIVHRD LKPRNIFLHG PDQQVKIGDF GLACADIIQK SADWTNRNGK GTPTHTSRVG TCLYASPEQL EGSEYDAKSD MYSLGVILLE LFQPFGTEME RATVLTGVRT GRIPESLSKR CPVQAKYIQL LTGRNAAQRP SALQLLQSEL FQTTGNVNLT LQMKIMEQEK EIEELKKQLS LLSQDKGLKR

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Abstract: EIF2AK1 Products

Synonyms: HCR Protein, Hri Protein, HRI Protein, wu:fj97h09 Protein, zgc:153232 Protein, eukaryotic translation initiation factor 2 alpha kinase 1 Protein, eukaryotic translation initiation factor 2-alpha kinase 1 Protein, eukaryotic translation initiation factor 2 alpha kinase 1 L homeolog Protein, EIF2AK1 Protein, eif2ak1 Protein, Eif2ak1 Protein, eif2ak1.L Protein

Background: Recommended name: Eukaryotic translation initiation factor 2-alpha kinase 1.
EC= 2.7.11.1.
Alternative name(s): Heme-controlled repressor.
Short name= HCR Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase Heme-regulated inhibitor Hemin-sensitive initiation factor 2-alpha kinase

UniProt: Q63185

Pathways: Hepatitis C