PEDF Protein
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- Target See all PEDF (SERPINF1) Proteins
- PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Mouse Pigment Epithelium-Derived Factor/PEDF/SERPIN F1
- Sequence
- MDPFFKVPVN KLAAAVSNFG YDLYRLRSSA SPTGNVLLSP LSVATALSAL SLGAEHRTES VIHRALYYDL ITNPDIHSTY KELLASVTAP EKNLKSASRI VFERKLRVKS SFVAPLEKSY GTRPRILTGN PRVDLQEINN WVQAQMKGKI ARSTREMPSA LSILLLGVAY FKGQWVTKFD SRKTTLQDFH LDEDRTVRVP MMSDPKAILR YGLDSDLNCK IAQLPLTGSM SIIFFLPLTV TQNLTMIEES LTSEFIHDID RELKTIQAVL TVPKLKLSFE GELTKSLQDM KLQSLFESPD FSKITGKPVK LTQVEHRAAF EWNEEGAGSS PSPGLQPVRL TFPLDYHLNQ PFLFVLRDTD TGALLFIGRI LDPSST
- Characteristics
- Recombinant Mouse Pigment epithelium-derived factor/SERPIN F1 is produced with our E. coli expression system. The target protein is expressed with sequence (Asp43Thr417 ) of Mouse SERPIN F1.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SERPINF1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- PEDF (SERPINF1) (serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
- Alternative Name
- SERPIN F1 (SERPINF1 Products)
- Synonyms
- EPC-1 Protein, OI12 Protein, OI6 Protein, PEDF Protein, MGC82984 Protein, SERPINF1 Protein, AI195227 Protein, Pedf Protein, Pedfl Protein, Sdf3 Protein, Dmrs91 Protein, zgc:92072 Protein, serpin family F member 1 Protein, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 Protein, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog Protein, serine (or cysteine) peptidase inhibitor, clade F, member 1 Protein, SERPINF1 Protein, serpinf1 Protein, serpinf1.L Protein, Serpinf1 Protein
- Background
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Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
Alternative Names: Pigment epithelium-derived factor, Pedf, Sdf3, Caspin, Serpin F1, Stromal cell-derived factor 3. - Molecular Weight
- 42 kDa
- UniProt
- P97298
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