proBNP Protein
-
- Target See all proBNP products
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purity
- > 95 % by SDS-PAGE
-
Pro-Brain Natriuretic Peptide (proBNP) (AA 27-121) protein (His tag)
proBNP Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Pro-Brain Natriuretic Peptide (proBNP) (AA 1-76) protein (His tag)proBNP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses ELISA, WB
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS (pH 7.5)
- Preservative
- Without preservative
- Storage
- 4 °C
-
- Target
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- Alternative Name
- Pro-BNP (proBNP Products)
- Synonyms
- BNP Protein, natriuretic peptide B Protein, NPPB Protein
- Background
- Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is released from the cardiac ventricles in response to increased wall tension. Rapid measurement of BNP is useful in establishing or excluding the diagnosis of congestive heart failure in patients with acute dyspnea. BNP is secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.
- Molecular Weight
- 17 kDa
-
