IL18RAP Protein (AA 20-356) (His tag)
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- Target See all IL18RAP Proteins
- IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-356
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IL18RAP protein is labelled with His tag.
- Purpose
- Recombinant Human IL-18 Receptor Accessory Protein/IL-18RAcP/IL-1R7 (C-6His)
- Sequence
- FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKRVDH HHHHH
- Characteristics
- Recombinant Human Interleukin-18 receptor accessory protein/IL18RAP is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe20-Arg356) of Human IL18RAP fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IL18RAP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))
- Alternative Name
- Interleukin-18 Receptor Accessory Protein/IL18RAP (IL18RAP Products)
- Synonyms
- IL18RAP Protein, ACPL Protein, CD218b Protein, CDw218b Protein, IL18RB Protein, interleukin 18 receptor accessory protein Protein, IL18RAP Protein, Il18rap Protein
- Background
- IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
- Molecular Weight
- 39.4 kDa
- UniProt
- O95256
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