TREML2 Protein (AA 19-268) (Fc Tag)
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- Target See all TREML2 Proteins
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-268
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This TREML2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human TREML2/TLT-2 (C-Fc)
- Sequence
- GPSADSVYTK VRLLEGETLS VQCSYKGYKN RVEGKVWCKI RKKKCEPGFA RVWVKGPRYL LQDDAQAKVV NITMVALKLQ DSGRYWCMRN TSGILYPLMG FQLDVSPAPQ SERNIPFTHL DNILKSGTVT TGQAPTSGPD APFTTGVMVF TPGLITLPRL LASTRPASKT GYSFTATSTT SQGPRRTMGS QTVTASPSNA RDSSAGPESI STKSGDLSTR SPTTGLCLTS RSLLNRLPSM PSIRHQDVYS VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
- Characteristics
- Recombinant Human Trem-like transcript 2 protein/TREML2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gly19-Ser268) of Human TREML2 fused with a FC tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TREML2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- Alternative Name
- Trem-Like Transcript 2 Protein/TREML2 (TREML2 Products)
- Synonyms
- TREM-B2V1 Protein, C6orf76 Protein, TLT-2 Protein, TLT2 Protein, dJ238O23.1 Protein, AW049306 Protein, Gm750 Protein, Tlt2 Protein, triggering receptor expressed on myeloid cells like 2 Protein, triggering receptor expressed on myeloid cells-like 2 Protein, TREML2 Protein, Treml2 Protein
- Sub Type
- Fusionprotein
- Background
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Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.
Alternative Names: Trem-like transcript 2 protein,TLT2, Triggering receptor expressed on myeloid cells-like protein 2, TLT2,C6orf76, - Molecular Weight
- 54.2 kDa
- UniProt
- Q5T2D2
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