IZUMO4 Protein (AA 16-214) (Fc Tag)
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- Target See all IZUMO4 Proteins
- IZUMO4 (IZUMO Family Member 4 (IZUMO4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-214
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IZUMO4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human Izumo Sperm-Egg Fusion Protein 4/ IZUMO4 (C-Fc)
- Sequence
- HGCLHCHSNF SKKFSFYRHH VNFKSWWVGD IPVSGALLTD WSDDTMKELH LAIPAKITRE KLDQVATAVY QMMDQLYQGK MYFPGYFPNE LRNIFREQVH LIQNAIIESR IDCQHRCGIF QYETISCNNC TDSHVACFGY NCESSAQWKS AVQGLLNYIN NWHKQDTSMS LVSPALRCLE PPHLANLTLE DAAECLKQHV DDIEGRMDEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK
- Characteristics
- Recombinant Human IZUMO4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 16-214) of Human IZUMO4 fused with a FC tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IZUMO4 (IZUMO Family Member 4 (IZUMO4))
- Alternative Name
- IZUMO4 (IZUMO4 Products)
- Synonyms
- C19orf36 Protein, IMAGE:4215339 Protein, 9030607L17Rik Protein, AI550407 Protein, IZUMO family member 4 Protein, IZUMO4 Protein, Izumo4 Protein
- Background
- Izumo sperm-egg fusion protein 4 is a sperm membrane protein which plays a key role in the fusion in the mouse. IZUMO4 has an N-terminal domain with significant homology to the N-terminal domain of Izumo.It belongs to the Izumo family . Izumo 4 is a soluble protein expressed in the testis and in other tissues. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or the cytoplasmic domain or both of Izumo 1 are required for the formation of multimers of higher order.
- Molecular Weight
- 50.1 kDa
- UniProt
- Q1ZYL8
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