ADIPOQ Protein (AA 19-244)

Catalog No. ABIN2017658

Product Details

Target: ADIPOQ (Adiponectin (ADIPOQ))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 19-244

Origin: Human

Source: Escherichia coli (E. coli)

Characteristics: ED50 < 5 μg/mL, measured by a cell growth inhibitory assay using M1 cells, corresponding to a specific activity of > 2x 10^2 units/mg.
AA 19-244, expressed with an N-terminal Met.

Purity: > 95 % as analyzed by SDS-PAGE and HPLC.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against 50 mM Tris, 150 mM NaCl, pH 8.0.

Storage: -80 °C

Storage Comment: Lyophilized recombinant human Adiponectin (rhAdiponectin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhAdiponectin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: Adiponectin (ADIPOQ Products)

Synonyms: ADP Protein, DCAF9 Protein, 6720489L24Rik Protein, 9330209L04Rik Protein, Adp Protein, Mamdc1 Protein, RNSVSP4U Protein, SVSIV1 Protein, Svp4 Protein, ACDC Protein, ACRP30 Protein, ADIPQTL1 Protein, ADPN Protein, APM-1 Protein, APM1 Protein, GBP28 Protein, apM-1 Protein, 30kDa Protein, APN Protein, Acdc Protein, Acrp30 Protein, Ad Protein, adipo Protein, apM1 Protein, ADN Protein, acrpl Protein, adipo-b Protein, adipoql Protein, zgc:153584 Protein, adipoq Protein, WD and tetratricopeptide repeats 1 Protein, MAM domain containing glycosylphosphatidylinositol anchor 2 Protein, seminal vesicle secretory protein 4 Protein, adiponectin, C1Q and collagen domain containing Protein, adiponectin, C1Q and collagen domain containing, b Protein, adiponectin, C1Q and collagen domain containing L homeolog Protein, WDTC1 Protein, Mdga2 Protein, Svs4 Protein, ADIPOQ Protein, Adipoq Protein, adipoqb Protein, adipoq.L Protein

Background: Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. The receptors of Adiponectin are seven-transmembrane G protein coupled receptors: Receptor 1 is expressed in skeletal muscle and Receptor 2 in liver. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes. Therefore, Adiponectin has promising potential as a pharmacological agent. Recombinant human Adiponectin (rhAdiponectin) produced in E. coli is a single non-glycosylated polypeptide chain containing 227 amino acids. A fully biologically active molecule, rhAdiponectin has a molecular mass of 24.7 kDa analyzed by reducing SDS-PAGE.
Synonyms: Acrp-30, GBP-28, Apm-1

Molecular Weight: 24.7 kDa, observed by reducing SDS-PAGE.

UniProt: Q15848