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CXCL3 Protein

CXCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN2017731
  • Target See all CXCL3 Proteins
    CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 4
    • 3
    • 1
    • 1
    Mouse
    Source
    • 12
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS
    Characteristics
    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/mL.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    < 1 EU/μg of rMuDCIP-1/CXCL3 as determined by LAL method.
    Top Product
    Discover our top product CXCL3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Buffer
    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • Target
    CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
    Abstract
    CXCL3 Products
    Synonyms
    CXCL3 Protein, CINC-2b Protein, GRO3 Protein, GROg Protein, MIP-2b Protein, MIP2B Protein, SCYB3 Protein, Cinc-2 Protein, Cinc2 Protein, Gm1960 Protein, Dcip1 Protein, C-X-C motif chemokine ligand 3 Protein, chemokine (C-X-C motif) ligand 3 Protein, CXCL3 Protein, Cxcl3 Protein
    Background
    Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2 beta (macrophage inflammatory protein 2 beta), or DCIP1 (dendritic cell inflammatory protein-1) in mouse, CINC2 (cytokineinduced neutrophil attractant 2) in rat, and GRO gamma (growth regulated oncogene gamma) in humans. It is an 8 kDa proinflammatory member of the CXC subfamily of heparinbinding chemokines, also called alpha chemokines. Mature mouse CXCL3 shares 88 % and 57 % amino acid (aa) sequence identity with rat and human CXCL3, respectively.
    Synonyms: DCIP-1 Murine, CXCL3 Murine
    Molecular Weight
    7.9 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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