GMFB Protein
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- Target See all GMFB products
- GMFB (Glia Maturation Factor, beta (GMFB))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- SESLVVCDVA EDLVEKLRKF RFRKETHNAA IIMKIDKDER LVVLDEELEG VSPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H
- Purity
- > 97 % by SDS-PAGE and HPLC analyses.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- < 1 EU/μg of rMuGMF-beta as determined by LAL method.
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Glia Maturation Factor, beta (GMFB) (Active) protein
GMFB Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Glia Maturation Factor, beta (GMFB) (AA 1-142) protein (His tag)GMFB Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glia Maturation Factor, beta (GMFB) (AA 1-154) protein (GST tag)GMFB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glia Maturation Factor, beta (GMFB) (AA 2-142) protein (His tag)Crystallography grade GMFB Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Buffer
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- Target
- GMFB (Glia Maturation Factor, beta (GMFB))
- Alternative Name
- Glia Maturation Factor-Beta(GMF-Beta) (GMFB Products)
- Synonyms
- fc25b01 Protein, zgc:56451 Protein, zgc:86831 Protein, wu:fa97c03 Protein, wu:fc25b01 Protein, GMFB Protein, DKFZp459J101 Protein, gmfb Protein, 3110001H22Rik Protein, 3110001O16Rik Protein, AI851627 Protein, C79176 Protein, D14Ertd630e Protein, GMF Protein, gmf-beta Protein, glia maturation factor, beta Protein, glia maturation factor beta Protein, Glia maturation factor beta Protein, glia maturation factor, beta L homeolog Protein, gmfb Protein, GMFB Protein, Gmfb Protein, EDI_093190 Protein, Tsp_04922 Protein, LOC100101176 Protein, gmfb.L Protein
- Background
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Glia maturation factor-beta(GMF-beta) coded by GMFb gene at chromosome 14 in mouse, is identical to human GMF-beta, with the exception of two amino acid residues. It is a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family, and plays an important role in the upstream regulation of excessive production and the releasing of proinflammatory cytokines/chemokines in brain cells, leading to the destruction of oligodendrocytes, the myelin forming cells, and neurons.
Synonyms: GMF-beta, Murine, - Molecular Weight
- 16.6 kDa, a single non-glycosylated polypeptide chain containing 141 amino acid residues.
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