CCL3 Protein (AA 27-92)
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- Target See all CCL3 Proteins
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-92
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Origin
- Human
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Source
- CHO Cells
- Characteristics
- ED50 < 100 ng/mL, measured in a calcium flux assay using CHO/G alpha 15 cells expressing CCR5.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product CCL3 Protein
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Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 1-92) protein (GST tag)
CCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) protein (His tag)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)CCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 3 (CCL3) (Active) proteinCCL3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) proteinCCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (GST tag)CCL3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 3 (CCL3) protein (His tag)CCL3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) (Active) protein (Biotin)CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) protein (His tag)Crystallography grade CCL3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human MIP-1 Alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human MIP-1 Alpha should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
- Alternative Name
- MIP-1 alpha (CCL3 Products)
- Synonyms
- MIP-1alpha Protein, G0S19-1 Protein, LD78ALPHA Protein, MIP-1-alpha Protein, MIP1A Protein, SCYA3 Protein, MIP-1a Protein, Scya3 Protein, AI323804 Protein, LD78alpha Protein, MIP1-(a) Protein, MIP1-alpha Protein, Mip1a Protein, CCL3L1 Protein, CCL3L3 Protein, chemokine (C-C motif) ligand 3 Protein, C-C motif chemokine ligand 3 Protein, CCL3 Protein, Ccl3 Protein
- Background
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MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, is a small inducible monokine belonging to the intercrine beta (chemokine CC) family. It binds to CCR1, CCR4 and CCR5, and participates in the host response to invading pathogens by regulating the trafficking and activation of inflammatory cells, such as macrophages, lymphocytes, NK cells and dendritic cells. MIP-1 alpha polymorphisms are associated with HIV susceptibility or resistance. Recombinant MIP-1 alpha induces a dose-dependent inhibition of HIV and SIV infection.
Synonyms: Macrophage Inflammatory Protein-1 alpha, CCL3, LD78 alpha - Molecular Weight
- 8-10 kDa, observed by reducing SDS-PAGE.
- UniProt
- P10147
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Autophagy
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