FGF9 Protein (AA 4-208) (Fc Tag)

Catalog No. ABIN2181090

Product Details

Target: FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))

Protein Type: Recombinant

Protein Characteristics: AA 4-208

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FGF9 protein is labelled with Fc Tag.

Sequence: AA 4-208

Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55 kDa under reducing (R) condition, and 110 kDa under non-reducing (NR) condition (SDS-PAGE).

Purity: >92 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))

Alternative Name: FGF-9 (FGF-9 Products)

Synonyms: Eks Protein, FGF-9 Protein, GAF Protein, HBFG-9 Protein, HBGF-9 Protein, SYNS3 Protein, XFGF-9 Protein, fgf9-A Protein, fibroblast growth factor 9 Protein, fibroblast growth factor 9 S homeolog Protein, Fgf9 Protein, FGF9 Protein, fgf9.S Protein

Background: Fibroblast growth factor 9 is also known as FGF9, GAF, HBFG-9, SYNS3, and is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF9 is also a mitogen for oligodendrocyte type 2 astrocyte progenitor cells, smooth muscle cells, pheochromocytoma PC12 cells, and BALB/3T3 fibroblasts. However, unlike FGF acidic and basic, FGF9 has no effect on human umbilical vein endothelial cells, and it has been demonstrated that FGF9 binds preferentially to the IIIc form of FGFR3. Although no typical signal sequence was found in FGF9, it is secreted efficiently after synthesis not in a conventional manner. In nervous system, FGF9 is produced mainly by neurons and may plays an important role in CNS development. FGF9 has been shown to interact with Fibroblast growth factor receptor 3.

Molecular Weight: 50.1 kDa