Glutaredoxin 1 Protein (GRX1) (AA 1-106) (His tag)
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- Target See all Glutaredoxin 1 (GRX1) Proteins
- Glutaredoxin 1 (GRX1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-106
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Glutaredoxin 1 protein is labelled with His tag.
- Sequence
- AA 1-106
- Characteristics
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 12.7 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GRX1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5 with 1 mM DTT
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase induces formation of C150-C154 intrasubunit disulfide bond in the active site of the enzyme." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 12, pp. 3167-3177, (2018) (PubMed).
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S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase induces formation of C150-C154 intrasubunit disulfide bond in the active site of the enzyme." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 12, pp. 3167-3177, (2018) (PubMed).
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- Target
- Glutaredoxin 1 (GRX1)
- Alternative Name
- Glutaredoxin 1 (GRX1 Products)
- Synonyms
- Glrx1 Protein, Grx Protein, grx Protein, wu:fc38f02 Protein, zgc:103707 Protein, GLRXL Protein, Grx1 Protein, TTase Protein, C86710 Protein, D13Wsu156e Protein, grx1 Protein, GLRX Protein, GRX Protein, GRX1 Protein, GLRX1 Protein, TTF Protein, glrx Protein, glutaredoxin Protein, glutaredoxin (thioltransferase) Protein, glutaredoxin Grx1 Protein, NrdH-redoxin Protein, Uncharacterized monothiol glutaredoxin F10D7.3 Protein, glutaredoxin-1 (Grx1) Protein, temporal expression: late Protein, glutaredoxin L homeolog Protein, Glrx Protein, glrx Protein, GLRX Protein, grx1 Protein, AF_RS07750 Protein, F10D7.3 Protein, AFUA_1G06100 Protein, NT01EI_2528 Protein, O2L Protein, glrx.L Protein
- Target Type
- Viral Protein
- Background
- Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.
- Molecular Weight
- 12.7 kDa
- NCBI Accession
- NP_001112362
- Pathways
- Cell RedoxHomeostasis
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