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Vasn Protein (AA 24-575) (His tag)

Vasn Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181892
  • Target See all Vasn Proteins
    Vasn (Vasorin (Vasn))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-575
    Origin
    • 9
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Vasn protein is labelled with His tag.
    Sequence
    AA 24-575
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.6 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product Vasn Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    Vasn (Vasorin (Vasn))
    Alternative Name
    Vasorin (Vasn Products)
    Synonyms
    MGC88956 Protein, SLITL2 Protein, 2610528G05Rik Protein, Atia Protein, Slitl2 Protein, vasorin Protein, vasn Protein, VASN Protein, CpipJ_CPIJ018010 Protein, CpipJ_CPIJ019764 Protein, Vasn Protein
    Background
    Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain. VASN is expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. VASN can interact selectively and non-covalently with TGF-beta, transform growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. In general, VASN may act as an inhibitor of TGF-beta signaling.
    Molecular Weight
    61.6 kDa
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