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VSIG4 Protein (AA 20-283) (His tag)

VSIG4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181925
  • Target See all VSIG4 Proteins
    VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-283
    Origin
    • 10
    • 3
    • 1
    Human
    Source
    • 9
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This VSIG4 protein is labelled with His tag.
    Sequence
    AA 20-283
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE).
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
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    Discover our top product VSIG4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
    Alternative Name
    VSIG4 (VSIG4 Products)
    Synonyms
    DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein
    Background
    V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.
    Molecular Weight
    30.1 kDa
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