CCL17 Protein

Catalog No. ABIN2469118

Product Details

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Characteristics: Biological activity was determined by its ability to chemoattract human T cells using a concentration range of 1.0 - 10.0 ng/mL.

Purity: < 98 % by SDS-PAGE gel and HPLC analyses.

Endotoxin Level: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Handling Advice: As with any protein, exposing TARC recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -20 °C

Storage Comment: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted TARC is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Expiry Date: 24 months

Target Details

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: TARC (CCL17 Products)

Synonyms: A-152E5.3 Protein, ABCD-2 Protein, SCYA17 Protein, TARC Protein, CCL17 Protein, Abcd-2 Protein, Scya17 Protein, Scya17l Protein, Tarc Protein, abcd2 Protein, C-C motif chemokine ligand 17 Protein, chemokine (C-C motif) ligand 17 Protein, ATP-binding cassette sub-family D member 2 Protein, CCL17 Protein, Ccl17 Protein, LOC100537809 Protein

Background: TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Gene ID: 6361

NCBI Accession: NP_002978

OMIM: 4506829

UniProt: Q92583