PLAUR Protein (His tag)
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- Target See all PLAUR Proteins
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLAUR protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA
- Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 μg/mL (100 μL/well ) can bind biotinylated human UPA with a linear ranger of 25 - 500 ng/mL.
- Purity
- >92 % as determined by SDS-PAGE.
- Top Product
- Discover our top product PLAUR Protein
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- Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Alternative Name
- CD87 (PLAUR Products)
- Synonyms
- Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
- Background
- Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
- Molecular Weight
- 32.1 kDa
- Gene ID
- 5329
- UniProt
- Q03405
- Pathways
- Inositol Metabolic Process
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