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PLAUR Protein (His tag)

PLAUR Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB, ELISA Active
Catalog No. ABIN2566452
  • Target See all PLAUR Proteins
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 27
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 23
    • 13
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLAUR protein is labelled with His tag.
    Application
    Western Blotting (WB), ELISA
    Characteristics

    Measured by its binding ability in a functional ELISA. Immobilized human uPAR at 5 μg/mL (100 μL/well ) can bind biotinylated human UPA with a linear ranger of 25 - 500 ng/mL.

    Purity
    >92 % as determined by SDS-PAGE.
    Top Product
    Discover our top product PLAUR Protein
  • Application Notes
    This recombinant protein can be used for WB, ELISA. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Alternative Name
    CD87 (PLAUR Products)
    Synonyms
    Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
    Background
    Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
    Molecular Weight
    32.1 kDa
    Gene ID
    5329
    UniProt
    Q03405
    Pathways
    Inositol Metabolic Process
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