Glypican 3 Protein (GPC3) (His tag)
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- Target See all Glypican 3 (GPC3) Proteins
- Glypican 3 (GPC3)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glypican 3 protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA
- Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized rh GPC3 / Glypican-3 at 5 μg/mL (100 μL/well ) can bind human bFGF / FGF2 with a linear ranger of 0. 16 - 3. 2 ng/mL.
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product GPC3 Protein
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- Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- Glypican 3 (GPC3)
- Alternative Name
- Glypican 3 (GPC3 Products)
- Synonyms
- GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
- Background
- Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
- Molecular Weight
- 61.6 kDa
- Gene ID
- 2719
- NCBI Accession
- NP_004475
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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