Antigen 85B Protein
Origin: Mycobacterium tuberculosis
Host: Escherichia coli (E. coli)
Recombinant
>90 %
EDA, SDS
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- Target
- Antigen 85B
- Protein Type
- Recombinant
- Origin
- Mycobacterium tuberculosis
- Source
- Escherichia coli (E. coli)
- Application
- Endotoxin Detection Assay (EDA), SDS-PAGE (SDS)
- Purity
- >90 %
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- The protein should be reconstituted in apirogenic sterile water or 1X PBS
- Buffer
- 1 % glycerol
- Storage
- 4 °C
-
- Target
- Antigen 85B
- Background
- The 30kD-secretory protein antigen 85B (Ag85B) is the most abundant protein exposed by Mycobacterium tuberculosis acting as a potent immunoprotective antigen. Ag85B induces a strong T-cell proliferation and the IFN- secretion in most healthy individuals exposed to M. tuberculosis, in BCG-vaccinated mice and humans. It has been shown that antibodies against Ag85B are more prevalent in active tuberculosis patients with decreased cellular immune response.
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